Description

tert-Butyl 2,8-Diazaspiro[4.5]Decan-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza-bicyclic structure. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily needed by R&D and production teams in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• CNS Drug Development: Serves as a scaffold for compounds targeting neurological receptors and pathways.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.
• Library Synthesis: A valuable component for creating diverse screening libraries in drug discovery.

Basic Information

Product Name	tert-Butyl 2,8-Diazaspiro[4.5]Decan-2-Carboxylate Hydrochloride
CAS No.	869976-20-5
Molecular Formula	C13H25N2O2·HCl
Molecular Weight	276.81 g/mol (Free base: 241.35 g/mol)
Synonyms	2,8-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride (1:1); 2-tert-Butoxycarbonyl-2,8-diazaspiro[4.5]decane hydrochloride; Boc-2,8-diazaspiro[4.5]decane HCl; tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate hydrochloride; 869976-20-5; 2,8-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,8-Diazaspiro[4.5]Decan-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0% (Total impurities ≤3.0%)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.