Description

tert-Butyl 4-(5-Chloro-2-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific molecular architecture. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used as a key building block for constructing complex molecular frameworks required for final Active Pharmaceutical Ingredients.
• Medicinal Chemistry R&D: Essential for structure-activity relationship (SAR) studies and lead optimization processes in drug discovery laboratories.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl 4-(5-Chloro-2-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	869937-73-5
Molecular Formula	C15H20ClN3O4
Molecular Weight	341.79 g/mol
Synonyms	1-Boc-4-(5-Chloro-2-nitrophenyl)piperazine; tert-Butyl 4-(5-chloro-2-nitrophenyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(5-chloro-2-nitrophenyl)piperazine; 869937-73-5; 4-(5-Chloro-2-nitrophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(5-Chloro-2-nitrophenyl)piperazine; N-Boc-4-(5-Chloro-2-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Chloro-2-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.