Description

(S)-1-Ethyl-5-Methylpiperazin-2-One is a high-purity, single-enantiomer chiral piperazinone derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex bioactive molecules. It is essential for research and production in the pharmaceutical and fine chemical industries, particularly for developing novel therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis to introduce specific three-dimensional configurations into target molecules.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries in drug discovery programs targeting G-protein-coupled receptors (GPCRs) and other biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex specialty chemicals, agrochemicals, and performance materials requiring high enantiomeric purity.
• Academic & R&D: Used in university and institutional laboratories for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	(S)-1-Ethyl-5-Methylpiperazin-2-One
CAS No.	869901-73-5
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(S)-1-Ethyl-5-methyl-2-piperazinone; (S)-1-Ethyl-5-methylpiperazin-2-one; (5S)-1-Ethyl-5-methylpiperazin-2-one; 1-Ethyl-5-methyl-(S)-piperazin-2-one; (S)-1-Ethyl-5-methyl-2-oxopiperazine; (S)-5-Methyl-1-ethylpiperazin-2-one; (S)-EMPO; Chiral 1-Ethyl-5-methylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our (S)-1-Ethyl-5-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.