Description

Ethyl 2-((tert-Butoxycarbonyl)Amino)-2-(Pyrazin-2-Yl)Acetate is a high-purity, protected amino acid derivative featuring a pyrazine heterocycle and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical pharmaceutical intermediate used in the synthesis of complex molecules, particularly in medicinal chemistry and peptide research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel drug candidates and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazine motifs.
• Peptide Chemistry: Used in the preparation of non-natural amino acid residues for peptide and peptidomimetic synthesis, leveraging the Boc-protected amine for selective deprotection.
• Medicinal Chemistry Research: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Chemical Biology Probes: Utilized in the development of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Fine Chemical Synthesis: An important precursor for the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific chiral centers.

Basic Information

Product Name	Ethyl 2-((tert-Butoxycarbonyl)Amino)-2-(Pyrazin-2-Yl)Acetate
CAS No.	869785-93-3
Molecular Formula	C13H19N3O4
Molecular Weight	281.31 g/mol
Synonyms	Ethyl Boc-2-amino-2-(pyrazin-2-yl)acetate; Ethyl N-Boc-2-amino-2-(2-pyrazinyl)acetate; 2-((tert-Butoxycarbonyl)amino)-2-(pyrazin-2-yl)acetic acid ethyl ester; N-(tert-Butoxycarbonyl)-2-(pyrazin-2-yl)glycine ethyl ester; Boc-Pyrazine-glycine ethyl ester; Boc-2-(2-Pyrazinyl)glycine ethyl ester; (R/S)-Ethyl 2-((tert-butoxycarbonyl)amino)-2-(pyrazin-2-yl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-((tert-Butoxycarbonyl)Amino)-2-(Pyrazin-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.