Description

2-(2-(Monomethoxytritylamino)Ethoxy)Ethanol is a specialized protected amino alcohol building block of significant importance in advanced organic synthesis. This compound is valued for its role in the controlled introduction of functionalized amino groups, particularly in the synthesis of complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications in oligonucleotide synthesis, peptide chemistry, and the development of novel drug conjugates.

Application

• Oligonucleotide Synthesis: A key intermediate in solid-phase phosphoramidite chemistry for the preparation of modified DNA/RNA strands.
• Peptide & Protein Modification: Used to introduce hydrophilic, spacer-linked amino functionalities for bioconjugation and labeling.
• Linker Chemistry: Serves as a versatile, protected linker molecule for attaching payloads in antibody-drug conjugates (ADCs) and other targeted therapies.
• Polymer & Dendrimer Synthesis: A functional monomer for creating specialized polymers with tailored amino group density and solubility profiles.
• Protecting Group Strategy: The monomethoxytrityl (MMT) group provides orthogonal protection for amines in multi-step synthetic sequences.
• Chemical Biology Probes: A precursor for synthesizing probes and tools used in biochemical and cellular research.

Basic Information

Product Name	2-(2-(Monomethoxytritylamino)Ethoxy)Ethanol
CAS No.	869308-44-1
Molecular Formula	C25H29NO4
Molecular Weight	407.50 g/mol
Synonyms	2-[2-[(4-Methoxyphenyl)diphenylmethylamino]ethoxy]ethanol; MMT-NH-(CH2)2-O-(CH2)2-OH; N-MMT-2,2'-Oxybis(ethylamine) alcohol derivative; 2-{2-[(4-Methoxytriphenylmethyl)amino]ethoxy}ethanol; Amino-PEG2-alcohol, MMT-protected; N-(2-(2-Hydroxyethoxy)ethyl)-4-methoxytritylamine
EINECS	Contact for details

Quality Control

Our 2-(2-(Monomethoxytritylamino)Ethoxy)Ethanol is manufactured under strict quality systems suitable for research and pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.