Description

(1S,3S,4S,5R,7R)-4-Chloroadamantan-2-One is a high-purity, stereochemically defined chlorinated adamantane derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, polycyclic structure and specific chlorine substitution make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its stable adamantane core for enhanced product durability.
• Material Science Research: Acts as a precursor for novel polymers and dendrimers with unique thermal and mechanical properties.
• Catalyst Ligand Development: The defined stereochemistry provides a scaffold for creating asymmetric catalysts used in enantioselective synthesis.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for electronics and high-performance materials.

Basic Information

Product Name	(1S,3S,4S,5R,7R)-4-Chloroadamantan-2-One
CAS No.	19543-61-4
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	4-Chloroadamantan-2-one; (1S,3S,4S,5R,7R)-4-Chlorotricyclo[3.3.1.13,7]decan-2-one; (-)-4-Chloroadamantan-2-one; 4-Chloro-2-adamantanone; 2-Adamantanone, 4-chloro-; (1S,3S,4S,5R,7R)-4-Chloro-2-adamantanone; 19543-61-4
EINECS	Contact for details

Quality Control

Our (1S,3S,4S,5R,7R)-4-Chloroadamantan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.