Description

2-Adamantanone, 4-Chloro-, (1S,4R)- is a high-purity, stereochemically defined chiral building block derived from the adamantane scaffold. This compound matters as a critical intermediate for advanced pharmaceutical research and fine chemical synthesis, offering a rigid, lipophilic framework for developing novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to leverage its unique three-dimensional structure.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective chemical reactions to construct complex molecular architectures.
• Agrochemical Research: Employed in the synthesis of novel, high-performance crop protection agents with potential enhanced stability and activity.
• Material Science Precursor: Acts as a building block for synthesizing specialty polymers, dendrimers, or metal-organic frameworks (MOFs) with tailored properties.
• Catalyst Ligand Development: Utilized to create novel chiral ligands for asymmetric catalysis in industrial chemical processes.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	2-Adamantanone, 4-Chloro-, (1S,4R)-
CAS No.	19301-54-3
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	(1S,4R)-4-Chloroadamantan-2-one; (-)-(1S,4R)-4-Chloro-2-adamantanone; 4-Chloro-2-adamantanone, (1S,4R)-; (1S,4R)-4-Chloro-2-tricyclo[3.3.1.13,7]decanone; 4-Chloro-2-adamantanone ((-)-(1S,4R)-form); Chiral 4-chloroadamantan-2-one
EINECS	Contact for details

Quality Control

Our 2-Adamantanone, 4-Chloro-, (1S,4R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.