Description

Melogliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, a class of compounds used in the management of type 2 diabetes. Its high selectivity and efficacy make it a valuable active pharmaceutical ingredient (API) for the development of advanced therapeutic formulations. This compound is primarily targeted at pharmaceutical manufacturers and research institutions engaged in metabolic disorder drug discovery and production.

Application

• Primary Active Pharmaceutical Ingredient (API) in the formulation of oral anti-diabetic medications.
• Key intermediate in advanced pharmaceutical research for next-generation DPP-4 inhibitors.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying the role of DPP-4 in glucose metabolism and related pathways.

Basic Information

Product Name	Melogliptin
CAS No.	868771-57-7
Molecular Formula	C₁₈H₂₁FN₆O₂
Molecular Weight	372.40 g/mol
Synonyms	Melogliptin; (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-4,6-dihydro-5H-pyrrolo[3,4-d]imidazol-5-yl]tetrahydro-2-furylmethanol; 2-({(2R,3S,5R)-5-[2-(Methylsulfonyl)-4,6-dihydro-5H-pyrrolo[3,4-d]imidazol-5-yl]-3-(2,5-difluorophenyl)tetrahydro-2-furyl}methoxy)ethanol; DPP-4 Inhibitor; GRC 8200
EINECS	Contact for details

Quality Control

Our Melogliptin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.