Description

1-Piperazinebutanenitrile, β-Oxo-4-Phenyl-α-(4-Tricyclo[3.3.1.13,7]Dec-1-Yl-2-Thiazolyl)- is a sophisticated heterocyclic compound featuring a unique adamantane-thiazole-piperazine scaffold. This complex molecular architecture makes it a highly valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies, particularly for targets involving central nervous system (CNS) or anti-infective pathways.
• Protease Inhibitor Development: The structural motifs suggest potential utility in the design of protease or kinase inhibitors.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in API manufacturing.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of proprietary compounds for biotechnology and pharmaceutical clients.
• Academic & Institutional Research: Used in universities and research institutes for exploratory chemistry and pharmacological studies.

Basic Information

Product Name	1-Piperazinebutanenitrile, β-Oxo-4-Phenyl-α-(4-Tricyclo[3.3.1.13,7]Dec-1-Yl-2-Thiazolyl)-
CAS No.	868269-74-3
Molecular Formula	C26H30N4OS
Molecular Weight	446.61 g/mol
Synonyms	4-(4-Adamantan-1-yl-1,3-thiazol-2-yl)-4-oxo-2-phenylbutanenitrile; 2-Phenyl-4-(4-tricyclo[3.3.1.13,7]dec-1-yl-1,3-thiazol-2-yl)-4-oxobutanenitrile; 4-(4-Adamantan-1-ylthiazol-2-yl)-4-oxo-2-phenylbutanenitrile; Adamantyl-thiazole-piperazine derivative; CAS 868269-74-3
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinebutanenitrile, β-Oxo-4-Phenyl-α-(4-Tricyclo[3.3.1.13,7]Dec-1-Yl-2-Thiazolyl)- adheres to stringent cGMP and ISO 9001 quality management principles. Every batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.