Description

2-(4-Boc-Piperazinyl)-2-(3-Methoxy-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a chiral acetic acid derivative. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Protease Inhibitor Development: Serves as a precursor in the synthesis of potential protease inhibitors due to its specific stereochemistry and functional groups.
• GPCR-Targeted Drug Synthesis: Employed in the preparation of compounds targeting G-protein-coupled receptors, where the piperazine scaffold is common.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic & Institutional Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3-Methoxy-Phenyl)Acetic Acid
CAS No.	868151-10-4
Molecular Formula	C18H26N2O5
Molecular Weight	350.41 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(3-methoxyphenyl)acetic acid; 2-(3-Methoxyphenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(3-methoxy-phenyl)acetic acid; (2R)-2-(4-Boc-piperazinyl)-2-(3-methoxy-phenyl)acetic acid (for chiral form); BOC-Piperazine-Phenylacetic Acid Derivative; tert-Butyl 4-(2-carboxy-2-(3-methoxyphenyl)ethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3-Methoxy-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided for every shipment, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.