Description

1-(3,5-Difluorobenzyl)Piperazine is a high-value, fluorinated piperazine derivative, a key building block in modern organic synthesis. Its molecular structure, featuring a difluorobenzyl group, is engineered to enhance the metabolic stability and binding affinity of target molecules, making it a critical intermediate for research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential CNS agents and advanced crop protection chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the difluorobenzyl moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	1-(3,5-Difluorobenzyl)Piperazine
CAS No.	868054-29-9
Molecular Formula	C11H14F2N2
Molecular Weight	212.24 g/mol
Synonyms	1-[(3,5-Difluorophenyl)methyl]piperazine; 3,5-Difluorobenzylpiperazine; N-[(3,5-Difluorophenyl)methyl]piperazine; 1-(3,5-Difluorobenzyl)piperazine; Piperazine, 1-[(3,5-difluorophenyl)methyl]-; 868054-29-9; 3,5-Difluoro-α-piperazinobenzyl
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.