Description

tert-Butyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its dual functional groups—a protected amine and a terminal hydroxyl—which make it a crucial building block for constructing complex molecular architectures. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), particularly in creating novel drug candidates with piperazine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Organic Synthesis Reagent: Used in the preparation of complex molecules, including ligands for catalysis and functionalized polymers.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group serves as a temporary protecting group for amines in multi-step synthetic sequences.
• Linker Molecule: The hydroxyl and protected amine functionalities allow it to act as a spacer or linker in bioconjugation and prodrug development.
• Agrochemical Research: Employed in the research and development of new crop protection agents and herbicides.
• Material Science: A precursor for specialty monomers and additives used in advanced polymeric materials.

Basic Information

Product Name	tert-Butyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate
CAS No.	867359-85-1
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	1-Boc-4-(2-hydroxyethyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-hydroxyethyl)piperazine; 4-(2-Hydroxyethyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(2-hydroxyethyl)-1-piperazinecarboxylate; N-Boc-4-(2-hydroxyethyl)piperazine; 2-(1-Boc-piperazin-4-yl)ethanol; 1-N-Boc-4-(2-hydroxyethyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.