Description

4-(4-Bromo-Benzoyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperazine derivative and a crucial synthetic intermediate in modern organic chemistry. This compound matters because it provides a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the 4-bromobenzoyl-piperazine moiety into novel molecular architectures.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides, where the piperazine ring can contribute to biological activity.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis services, enabling the production of specialized compounds for research and development.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying biological pathways and protein function, leveraging its reactive handles for conjugation.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries used in screening campaigns to identify new bioactive molecules.

Basic Information

Product Name	4-(4-Bromo-Benzoyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	867333-30-0
Molecular Formula	C16H21BrN2O3
Molecular Weight	369.26 g/mol
Synonyms	1-Boc-4-(4-Bromobenzoyl)piperazine; tert-Butyl 4-(4-bromobenzoyl)piperazine-1-carboxylate; 4-(4-Bromobenzoyl)piperazine-1-carboxylic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonyl)-4-(4-bromobenzoyl)piperazine; N-Boc-4-(4-Bromobenzoyl)piperazine; Piperazine-1-carboxylic acid, 4-(4-bromobenzoyl)-, 1,1-dimethylethyl ester; 4-(p-Bromobenzoyl)-1-piperazinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 4-(4-Bromo-Benzoyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are available upon request. Our quality management system supports the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.