Description

2-((3-Chloropyrazin-2-Yl)Methyl)Isoindoline-1,3-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyrazine and isoindoline-1,3-dione (phthalimide) moieties. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific modes of action.
• Chemical Biology Probe Development: Used in medicinal chemistry to create molecular probes for studying enzyme inhibition and protein-ligand interactions.
• Material Science: Potential monomer or additive in the research of specialty polymers with specific electronic or thermal properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services.

Basic Information

Product Name	2-((3-Chloropyrazin-2-Yl)Methyl)Isoindoline-1,3-Dione
CAS No.	867165-55-7
Molecular Formula	C₁₃H₈ClN₃O₂
Molecular Weight	273.67 g/mol
Synonyms	N-[(3-Chloro-2-pyrazinyl)methyl]phthalimide; 1,3-Isoindolinedione, 2-[(3-chloro-2-pyrazinyl)methyl]-; 2-[(3-Chloro-2-pyrazinyl)methyl]-1H-isoindole-1,3(2H)-dione; 3-Chloro-2-(phthalimidomethyl)pyrazine; (3-Chloropyrazin-2-yl)methyl phthalimide
EINECS	Contact for details

Quality Control

Every batch of 2-((3-Chloropyrazin-2-Yl)Methyl)Isoindoline-1,3-Dione is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development use under current Good Manufacturing Practice (cGMP) principles where required. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.