Description

Ethyl 2-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Thiazole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine-thiazole core structure. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Protease Inhibitor Development: Serves as a precursor in the synthesis of molecules targeting various protease enzymes.
• Kinase Inhibitor Scaffold: The thiazole-piperazine structure is a valuable core for developing potential kinase inhibitors.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	Ethyl 2-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Thiazole-4-Carboxylate
CAS No.	867065-53-0
Molecular Formula	C15H23N3O4S
Molecular Weight	341.42 g/mol
Synonyms	Ethyl 2-[4-(tert-Butoxycarbonyl)piperazin-1-yl]-1,3-thiazole-4-carboxylate; 4-Carboxyethyl-2-(4-Boc-piperazinyl)thiazole; 1-Boc-4-(4-(ethoxycarbonyl)thiazol-2-yl)piperazine; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)thiazole-4-carboxylic acid ethyl ester; Boc-Pip-Thz-OEt; BOC-Piperazinyl-Thiazole-Carboxylate Ethyl Ester; CAS 867065-53-0
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Thiazole-4-Carboxylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.