Description

1,2-Dihydro-n-[(3-Endo)-8-[(2R)-2-Hydroxy-3-[Methyl(Methylsulfonyl)Amino]Propyl]-8-Azabicyclo[3.2.1]Oct-3-Yl]-1-(1-Methylethyl)-2-Oxo-3-Quinolinecarboxamide is a sophisticated, high-purity organic compound featuring a complex bicyclic and quinoline-based molecular architecture. This compound is of significant interest for its potential as a key pharmaceutical intermediate or advanced research chemical in the development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies, particularly in areas targeting specific enzyme or receptor interactions.
• Process Development & Scale-up: Employed in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs) for preclinical and clinical trials.
• Biochemical Research: May be utilized as a tool compound in biochemical assays to study biological pathways and mechanisms of action.
• Custom Synthesis: Acts as a substrate for further chemical modifications to create specialized libraries of analogs for high-throughput screening.

Basic Information

Product Name	1,2-Dihydro-n-[(3-Endo)-8-[(2R)-2-Hydroxy-3-[Methyl(Methylsulfonyl)Amino]Propyl]-8-Azabicyclo[3.2.1]Oct-3-Yl]-1-(1-Methylethyl)-2-Oxo-3-Quinolinecarboxamide
CAS No.	866933-46-2
Molecular Formula	C28H38N4O5S
Molecular Weight	542.69 g/mol
Synonyms	8-[(2R)-2-Hydroxy-3-[[(Methylsulfonyl)methylamino]propyl]-8-azabicyclo[3.2.1]oct-3-yl 1,2-dihydro-1-isopropyl-2-oxo-3-quinolinecarboxamide (3-endo); (3-endo)-8-[(2R)-2-Hydroxy-3-[[(Methylsulfonyl)methylamino]propyl]-8-azabicyclo[3.2.1]oct-3-yl 1,2-dihydro-1-isopropyl-2-oxo-3-quinolinecarboxamide; 866933-46-2; UNII-9K8F8P4A4S; 9K8F8P4A4S; 1,2-Dihydro-N-[(3-endo)-8-[(2R)-2-hydroxy-3-[methyl(methylsulfonyl)amino]propyl]-8-azabicyclo[3.2.1]oct-3-yl]-1-(1-methylethyl)-2-oxo-3-quinolinecarboxamide.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support development projects requiring material that meets ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability. The container should be kept in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.