Description

5-(4-Methyl-Piperazin-1-Yl)-Indan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a unique indanone-piperazine hybrid structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization, enabling the creation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	5-(4-Methyl-Piperazin-1-Yl)-Indan-1-One
CAS No.	866849-23-2
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	5-(4-Methylpiperazin-1-yl)-2,3-dihydro-1H-inden-1-one; 1-(4-Methylpiperazin-1-yl)indan-5-one; 5-(4-Methyl-1-piperazinyl)-1-indanone; 866849-23-2; 5-(4-Methylpiperazin-1-yl)indan-1-one; 1-Indanone, 5-(4-methyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 5-(4-Methyl-Piperazin-1-Yl)-Indan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.