Description

3-Methyl-1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperazine is a high-value, heterocyclic organic compound featuring a piperazine core substituted with a methyl group and a trifluoromethylpyridine moiety. This structure makes it a critical pharmaceutical intermediate and building block for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine group.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final chemical structure of APIs requiring a specific piperazine-based pharmacophore.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for metal-catalyzed reactions or as a component in organocatalysts.

Basic Information

Item	Detail
Product Name	3-Methyl-1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperazine
CAS No.	866785-24-2
Molecular Formula	C11H14F3N3
Molecular Weight	245.25 g/mol
Synonyms	3-Methyl-1-(5-trifluoromethyl-2-pyridyl)piperazine; 1-(5-(Trifluoromethyl)pyridin-2-yl)-3-methylpiperazine; 2-(3-Methylpiperazin-1-yl)-5-(trifluoromethyl)pyridine; 866785-24-2; 3-Methyl-1-(5-(trifluoromethyl)-2-pyridinyl)piperazine; 3-Methyl-1-[5-(trifluoromethyl)-2-pyridyl]piperazine
EINECS	Contact for details

Quality Control

Our 3-Methyl-1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.