Description

1-(2-Benzenesulfonyl-Ethyl)Piperazine 2Hcl is a high-purity, functionalized piperazine derivative primarily used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its sulfonyl and piperazine functionalities.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical space and structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex organic molecules in pilot plants and manufacturing settings.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1-(2-Benzenesulfonyl-Ethyl)Piperazine 2Hcl
CAS No.	866588-15-0
Molecular Formula	C12H18N2O2S • 2HCl
Molecular Weight	339.27 g/mol (as free base: 254.35 g/mol)
Synonyms	1-[2-(Phenylsulfonyl)ethyl]piperazine dihydrochloride; N-(2-Benzenesulfonylethyl)piperazine dihydrochloride; 1-(2-(Phenylsulfonyl)ethyl)piperazine hydrochloride (1:2); Piperazine, 1-[2-(phenylsulfonyl)ethyl]-, dihydrochloride; 866588-15-0; Benzenesulfonylethyl piperazine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(2-Benzenesulfonyl-Ethyl)Piperazine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.