Description

Pyrazinamine, 3-(Chloromethyl)-6-Methyl- (9Ci) is a specialized heterocyclic building block featuring a reactive chloromethyl group on the pyrazine core. This compound matters for its role as a versatile intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its reactive site for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs), due to its functionalizable pyrazine structure.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	Pyrazinamine, 3-(Chloromethyl)-6-Methyl- (9Ci)
CAS No.	866585-60-6
Molecular Formula	C6H8ClN3
Molecular Weight	157.60 g/mol
Synonyms	3-(Chloromethyl)-6-methylpyrazin-2-amine; 6-Methyl-3-(chloromethyl)pyrazin-2-amine; 2-Amino-3-(chloromethyl)-6-methylpyrazine; (3-Chloromethyl-6-methyl-pyrazin-2-yl)-amine; 3-Chloromethyl-6-methyl-2-pyrazinamine
EINECS	Contact for details

Quality Control

Our Pyrazinamine, 3-(Chloromethyl)-6-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.