Description

1-Phenoxy-3-[4-(2-Pyrimidinyl)Piperazino]-2-Propanol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) and cardiovascular fields. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting serotonin and adrenergic receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Development: Serves as a critical reference standard and starting material for scaling up synthetic routes under GMP conditions.
• Biochemical Research: Potential ligand or tool compound for in vitro pharmacological assays and receptor binding studies.
• Fine Chemical Synthesis: Intermediate for the production of more complex, specialty molecules with specific biological activities.

Basic Information

Product Name	1-Phenoxy-3-[4-(2-Pyrimidinyl)Piperazino]-2-Propanol
CAS No.	866135-56-0
Molecular Formula	C17H22N4O2
Molecular Weight	314.38 g/mol
Synonyms	1-Phenoxy-3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-ol; 2-Propanol, 1-phenoxy-3-[4-(2-pyrimidinyl)-1-piperazinyl]-; 1-Phenoxy-3-(4-pyrimidin-2-ylpiperazin-1-yl)-2-propanol; 3-[4-(Pyrimidin-2-yl)piperazin-1-yl]-1-phenoxypropan-2-ol; Phenoxypropanol piperazinylpyrimidine derivative
EINECS	Contact for details

Quality Control

Our 1-Phenoxy-3-[4-(2-Pyrimidinyl)Piperazino]-2-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.