Description

(-)-(3R)-Quinuclidin-3-Yl (1R)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline-2-Carboxylate (-)-(2S,3S)-Tartrate CAS NO 865813-82-7 is a high-purity, chiral chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) for the synthesis of novel therapeutics targeting the central nervous system. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in the discovery of new drugs. Our supply ensures the stringent quality and stereochemical purity required for successful preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in neuroscience.
• Neurological Research: Used in the development of compounds targeting specific receptors in the central nervous system.
• Active Pharmaceutical Ingredient (API): Serves as the core active component in investigational new drug (IND) applications.
• Asymmetric Synthesis: Employed in stereoselective chemical reactions to create complex molecular architectures.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical labs.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	(-)-(3R)-Quinuclidin-3-Yl (1R)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline-2-Carboxylate (-)-(2S,3S)-Tartrate
CAS No.	865813-82-7
Molecular Formula	C29H34N2O6
Molecular Weight	506.60 g/mol
Synonyms	(3R)-Quinuclidin-3-yl (1R)-1,2,3,4-tetrahydro-1-phenylisoquinoline-2-carboxylate (2S,3S)-tartrate; (R)-Quinuclidin-3-yl (R)-1,2,3,4-tetrahydro-1-phenylisoquinoline-2-carboxylate (2S,3S)-tartrate; (-)-Quinuclidin-3-yl (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate (2S,3S)-tartrate; QN-THIQ Tartrate; QN-THIQ-(2S,3S)-Tartrate; (1R,3R)-QN-THIQ Tartrate; (R,R)-QN-THIQ (2S,3S)-Tartrate
EINECS	Contact for details

Quality Control

Our (-)-(3R)-Quinuclidin-3-Yl (1R)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline-2-Carboxylate (-)-(2S,3S)-Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and residual solvent analysis to ensure compliance with ICH Q3 guidelines. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.