Description

tert-Butyl 4-(3-Bromobenzyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a Boc (tert-butoxycarbonyl) group. This compound is of significant value for its role as a versatile building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those containing functionalized piperazine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• CNS Drug Development: Serves as a building block for potential therapeutics targeting neurological and psychiatric conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of specialized compounds for clients.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and protein interactions.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	tert-Butyl 4-(3-Bromobenzyl)Piperazine-1-Carboxylate
CAS No.	865314-27-8
Molecular Formula	C16H23BrN2O2
Molecular Weight	355.27 g/mol
Synonyms	1-Boc-4-(3-Bromobenzyl)piperazine; 4-(3-Bromobenzyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(3-bromophenyl)methyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(3-bromobenzyl)piperazine; N-Boc-4-(3-bromobenzyl)piperazine; 865314-27-8; 4-(3-Bromobenzyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Bromobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D, including ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.