Description

(R)-Methyl 2-(Piperidin-3-Yl)Acetate Hydrochloride CAS NO 865157-03-5 is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. Its value lies in providing a stereochemically defined piperidine scaffold, which is a privileged structure in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of central nervous system (CNS) active drugs, receptor modulators, and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require specific stereochemistry for optimal activity.
• Chemical Research & Development: Serves as a versatile precursor in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	(R)-Methyl 2-(Piperidin-3-Yl)Acetate Hydrochloride
CAS No.	865157-03-5
Molecular Formula	C8H16ClNO2
Molecular Weight	193.67 g/mol
Synonyms	(R)-Methyl 2-(3-Piperidyl)acetate hydrochloride; Methyl (R)-2-(piperidin-3-yl)acetate hydrochloride; (R)-3-(2-Methoxy-2-oxoethyl)piperidine hydrochloride; (R)-Piperidine-3-acetic acid methyl ester hydrochloride; (3R)-2-(Methoxycarbonylmethyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Methyl 2-(Piperidin-3-Yl)Acetate Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.