Description

4-Iodo-n-[3-(4-Methyl-Piperazin-1-Yl)-Propyl]-Benzenesulfonamide Dihydrochloride CAS NO 864875-99-0 is a high-purity, functionalized sulfonamide derivative designed for advanced research and development. This compound is of significant interest as a key synthetic intermediate or a potential pharmacologically active scaffold in medicinal chemistry programs. It is primarily targeted at pharmaceutical R&D teams, contract research organizations (CROs), and academic laboratories engaged in drug discovery, particularly in areas requiring structurally complex, iodinated aromatic building blocks.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable sulfonamide and piperazine moieties.
• Biochemical Probe Development: Potential utility in developing molecular probes for studying enzyme inhibition or receptor binding, leveraging the iodine atom for labeling.
• Chemical Biology: Employed in the discovery and development of chemical tools for modulating biological pathways.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary compounds for client-specific R&D projects.
• Academic Research: Used in university laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Iodo-n-[3-(4-Methyl-Piperazin-1-Yl)-Propyl]-Benzenesulfonamide Dihydrochloride
CAS No.	864875-99-0
Molecular Formula	C14H23IN4O2S · 2HCl
Molecular Weight	547.24 g/mol (Free base: 414.33 g/mol)
Synonyms	4-Iodo-N-[3-(4-methylpiperazin-1-yl)propyl]benzenesulfonamide dihydrochloride; Benzenesulfonamide, 4-iodo-N-[3-(4-methyl-1-piperazinyl)propyl]-, dihydrochloride; 864875-99-0; 4-Iodo-N-(3-(4-methylpiperazin-1-yl)propyl)benzenesulfonamide 2HCl; N-[3-(4-Methylpiperazin-1-yl)propyl]-4-iodobenzenesulfonamide dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodo-n-[3-(4-Methyl-Piperazin-1-Yl)-Propyl]-Benzenesulfonamide Dihydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is verified against stringent in-house specifications using advanced techniques such as HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.