Description

1-Benzyl-4-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, synthetically derived organic compound primarily used as a key intermediate in advanced pharmaceutical research and development. Its value lies in its specific molecular architecture, which is crucial for constructing complex active pharmaceutical ingredients (APIs) and novel therapeutic agents. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Chemical Research & Development: Used as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and commercial manufacturing processes for active pharmaceutical ingredients (APIs).
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Employed in university and institutional laboratories for studying organic reaction mechanisms and developing new synthetic methodologies.
• Custom Synthesis: A foundational compound for contract research and manufacturing organizations (CROs/CMOs) producing specialized chemicals for clients.

Basic Information

Product Name	1-Benzyl-4-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	864759-66-0
Molecular Formula	C18H22N2O3S • HCl
Molecular Weight	382.90 g/mol
Synonyms	1-Benzyl-4-(2-methoxybenzenesulfonyl)piperazine hydrochloride; 1-Benzyl-4-(2-methoxyphenylsulfonyl)piperazine HCl; 2-Methoxy-N-(1-benzylpiperidin-4-yl)benzenesulfonamide hydrochloride (related); 864759-66-0; BMS-986142 intermediate (potential); Piperazine, 1-benzyl-4-[(2-methoxyphenyl)sulfonyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.