Description

4-(4-Bromo-2-Ethyl-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its benzenesulfonyl-piperazine core structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific receptor sites.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new compounds with improved efficacy and safety profiles.
• API Development: Serves as a precursor in the production of active pharmaceutical ingredients for preclinical and clinical trial materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Biochemical Reagent: May be utilized in biochemical assays and as a tool compound for probing biological pathways in academic and industrial research settings.

Basic Information

Product Name	4-(4-Bromo-2-Ethyl-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	864759-59-1
Molecular Formula	C₁₂H₁₈BrClN₂O₂S
Molecular Weight	369.70 g/mol
Synonyms	4-(4-Bromo-2-ethylbenzenesulfonyl)piperazine hydrochloride; 1-(4-Bromo-2-ethylphenyl)sulfonylpiperazine hydrochloride; Piperazine, 1-[(4-bromo-2-ethylphenyl)sulfonyl]-, hydrochloride (1:1); 864759-59-1; 4-(4-Bromo-2-ethyl-benzenesulfonyl)-piperazine HCl
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-2-Ethyl-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material produced under current Good Manufacturing Practice (cGMP) guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.