Description

(2-[1,4]Diazepan-1-Yl-1-Methyl-2-Oxo-Ethyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules, particularly those targeting neurological and psychiatric pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this specialized intermediate to streamline the synthesis of novel active pharmaceutical ingredients (APIs) and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Peptidomimetic Synthesis: Used to incorporate modified diazepane-based amino acid structures into peptide backbones to enhance stability and bioavailability.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRAM) for producing bespoke compounds for client projects.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological mechanisms.

Basic Information

Product Name	(2-[1,4]Diazepan-1-Yl-1-Methyl-2-Oxo-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	864754-26-7
Molecular Formula	C14H25N3O3
Molecular Weight	283.37 g/mol
Synonyms	tert-Butyl N-[(2S)-1-[(3S)-1,4-diazepan-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate; Boc-Diazepane Amino Acid Ester; 1-Boc-2-(1,4-diazepan-1-yl)-3-methyl-2-oxopropylamine; (S)-2-((S)-1,4-Diazepane-1-carbonyl)-3-methylbutylcarbamic acid tert-butyl ester; N-Boc-2-(1,4-diazepan-1-yl)-3-methyl-2-oxopropylamine; 864754-26-7; (2-(1,4-Diazepan-1-yl)-1-methyl-2-oxoethyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of (2-[1,4]Diazepan-1-Yl-1-Methyl-2-Oxo-Ethyl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.