Description

4-(4-Piperazin-2-Yl-Phenyl)Morpholine is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining piperazine and morpholine moieties. This compound matters for its critical role as a key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation therapeutic agents with targeted efficacy.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block for the synthesis of novel drug candidates, especially in CNS and oncology research pipelines.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex nitrogen-containing heterocycles in medicinal chemistry.
• Research & Development: Essential for academic and industrial research focused on developing new pharmacophores and studying structure-activity relationships (SAR).
• Custom Synthesis: Used by contract research and manufacturing organizations (CRMOs) for the production of bespoke compounds and reference standards.
• Ligand & Catalyst Development: Potential application in the design of novel ligands for catalytic systems or as a scaffold in chemical biology.

Basic Information

Item	Detail
Product Name	4-(4-Piperazin-2-Yl-Phenyl)Morpholine
CAS No.	864685-27-8
Molecular Formula	C14H21N3O
Molecular Weight	247.34 g/mol
Synonyms	4-(4-(Piperazin-1-yl)phenyl)morpholine; 4-[4-(Piperazin-1-yl)phenyl]morpholine; 1-[4-(Morpholin-4-yl)phenyl]piperazine; 4-(4-Piperazinophenyl)morpholine; 4-Morpholino-N-(piperazin-1-yl)aniline; UNII-7J6K6CKK0F; 7J6K6CKK0F; BDBM50111635; AKOS025310647
EINECS	Contact for details

Quality Control

Our 4-(4-Piperazin-2-Yl-Phenyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.