Description

1-(2-Fluorobenzyl)Piperidin-3-Ol is a high-purity fluorinated piperidine derivative, a crucial building block in modern organic synthesis. This compound is valued for its unique molecular architecture, which combines a fluorinated benzyl group with a functionalized piperidine ring, enabling precise modifications in complex chemical pathways. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-(2-Fluorobenzyl)Piperidin-3-Ol
CAS No.	864388-88-5
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	3-Piperidinol, 1-[(2-fluorophenyl)methyl]-; 1-[(2-Fluorophenyl)methyl]piperidin-3-ol; 1-(2-Fluorobenzyl)-3-hydroxypiperidine; 1-(2-Fluorobenzyl)piperidin-3-ol; 864388-88-5; 2-Fluorobenzyl piperidin-3-ol; 3-Hydroxy-1-(2-fluorobenzyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)Piperidin-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced applications and can provide material tailored to specific pharmacopeial or internal specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.