Description

tert-Butyl 4-(4-(Hydroxymethyl)Phenyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a hydroxymethylphenyl group and a Boc-protected amine, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of active pharmaceutical ingredients (APIs).
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A versatile substrate for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in universities and research institutes for methodological development and the synthesis of complex organic molecules.

Basic Information

Product Name	tert-Butyl 4-(4-(Hydroxymethyl)Phenyl)Piperidine-1-Carboxylate
CAS No.	864359-18-2
Molecular Formula	C17H25NO3
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-(4-(hydroxymethyl)phenyl)piperidine; 4-(4-Hydroxymethylphenyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[4-(hydroxymethyl)phenyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-(hydroxymethyl)phenyl)piperidine; 4-(4-Hydroxymethyl-phenyl)-piperidine-1-carboxylic acid tert-butyl ester; 864359-18-2; BOC-4-(4-Hydroxymethylphenyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-(Hydroxymethyl)Phenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.