Description

Piperazine, 1-(1-Methyl-3-Azetidinyl)- is a specialized heterocyclic organic compound featuring a piperazine core fused with a methyl-substituted azetidine ring. This unique molecular architecture makes it a valuable and versatile pharmaceutical intermediate and building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Building Block: Used to introduce the constrained piperazine-azetidine pharmacophore to explore structure-activity relationships (SAR) and optimize drug-like properties.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Employed in the creation of tool compounds for studying biological pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	Piperazine, 1-(1-Methyl-3-Azetidinyl)-
CAS No.	864350-81-2
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	1-(1-Methylazetidin-3-yl)piperazine; 1-Methyl-3-(piperazin-1-yl)azetidine; 1-Methyl-3-piperazin-1-yl-azetidine; 1-(1-Methyl-3-azetidinyl)piperazine; 3-Piperazin-1-yl-1-methyl-azetidine; Azetidine, 1-methyl-3-(1-piperazinyl)-; 864350-81-2
EINECS	Contact for details

Quality Control

We maintain a strict quality management system aligned with ICH guidelines to ensure batch-to-batch consistency. Our Piperazine, 1-(1-Methyl-3-Azetidinyl)- is produced under controlled conditions and undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.