Description

tert-Butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate is a high-purity, protected azetidine-piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the creation of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers requiring reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological pathways and protein function.
• Custom Synthesis: A fundamental component for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions involving nitrogen heterocycles.

Basic Information

Product Name	tert-Butyl 3-(4-Benzylpiperazin-1-yl)azetidine-1-carboxylate
CAS No.	864248-52-2
Molecular Formula	C19H29N3O2
Molecular Weight	331.46 g/mol
Synonyms	1-Boc-3-(4-benzylpiperazin-1-yl)azetidine; tert-Butyl 3-(4-benzyl-1-piperazinyl)-1-azetidinecarboxylate; 3-(4-Benzylpiperazin-1-yl)azetidine-1-carboxylic acid tert-butyl ester; 1-(1,1-Dimethylethyl) 3-[4-(phenylmethyl)-1-piperazinyl]-1-azetidinecarboxylate; 864248-52-2; AZETIDINE-1-CARBOXYLIC ACID, 3-(4-BENZYLPIPERAZIN-1-YL)-, 1,1-DIMETHYLETHYL ESTER
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.