Description

4-(4-Acetyl-Piperazin-1-Yl)-2-Fluoroaniline is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage its fluoroaniline and piperazine motifs.
• Chemical Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Academic & R&D Laboratories: Employed in university and corporate research settings for exploring new chemical entities and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	4-(4-Acetyl-Piperazin-1-Yl)-2-Fluoroaniline
CAS No.	864146-95-2
Molecular Formula	C12H16FN3O
Molecular Weight	237.28 g/mol
Synonyms	2-Fluoro-4-(4-acetylpiperazin-1-yl)aniline; 1-[4-Amino-3-fluorophenyl]-4-acetylpiperazine; 4-(4-Acetyl-1-piperazinyl)-2-fluoroaniline; 2-Fluoro-4-(4-acetyl-1-piperazinyl)benzenamine; 864146-95-2; 4-(4-Acetylpiperazin-1-yl)-2-fluoroaniline; 2-Fluoro-4-(4-acetylpiperazino)aniline
EINECS	Contact for details

Quality Control

Our 4-(4-Acetyl-Piperazin-1-Yl)-2-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.