Description

2-[(4-Methylpiperazin-1-Yl)Methyl]Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a benzonitrile core substituted with a methylpiperazine moiety. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a key structural component in the synthesis of potential kinase inhibitors for cancer therapy.
• CNS Drug Synthesis: Employed in the research and development of compounds targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-[(4-Methylpiperazin-1-Yl)Methyl]Benzonitrile
CAS No.	864069-00-1
Molecular Formula	C13H17N3
Molecular Weight	215.30 g/mol
Synonyms	2-((4-Methylpiperazin-1-yl)methyl)benzonitrile; 1-[(2-Cyanophenyl)methyl]-4-methylpiperazine; 2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile; 2-(4-Methylpiperazin-1-ylmethyl)benzonitrile; 2-Cyano-N-(4-methylpiperazin-1-yl)benzylamine; 864069-00-1; Benzonitrile, 2-[(4-methyl-1-piperazinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 2-[(4-Methylpiperazin-1-Yl)Methyl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.