Description

(R,S)-4-Boc-3-Carboxymethyl-Piperazin-2-One is a versatile and high-purity chiral piperazinone derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex pharmacologically active molecules, particularly in the development of new therapeutic agents. This compound is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly protease inhibitors and other bioactive heterocycles.
• Peptidomimetics Research: Used to construct constrained peptide analogs and peptidomimetic scaffolds for drug discovery programs.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to introduce complex molecular frameworks.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and APIs.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical entities.

Basic Information

Product Name	(R,S)-4-Boc-3-Carboxymethyl-Piperazin-2-One
CAS No.	863307-54-4
Molecular Formula	C12H20N2O5
Molecular Weight	272.30 g/mol
Synonyms	4-(tert-Butoxycarbonyl)-3-(carboxymethyl)-2-oxopiperazine; 3-(Carboxymethyl)-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-2-one; 4-Boc-3-carboxymethyl-2-piperazinone; tert-Butyl 3-(carboxymethyl)-2-oxopiperazine-1-carboxylate; 1-Boc-3-carboxymethyl-piperazin-2-one; (RS)-1-Boc-3-carboxymethylpiperazin-2-one; 4-Boc-3-(carboxymethyl)piperazin-2-one; 1-N-Boc-3-carboxymethyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our (R,S)-4-Boc-3-Carboxymethyl-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.