Description

(R)-1-(1-(4-Fluorophenyl)Ethyl)Piperazine is a high-purity, chiral piperazine derivative of significant importance in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for synthesizing active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of novel therapeutics, particularly within the central nervous system (CNS) and other specialized drug classes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for CNS-targeting drugs.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Serves as a starting material for producing compounds used in pharmacological and toxicological studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.
• Chemical Biology: Employed in the design and synthesis of molecular probes to study biological systems and enzyme functions.

Basic Information

Product Name	(R)-1-(1-(4-Fluorophenyl)Ethyl)Piperazine
CAS No.	862270-48-2
Molecular Formula	C12H17FN2
Molecular Weight	208.28 g/mol
Synonyms	(R)-1-[1-(4-Fluorophenyl)ethyl]piperazine; (R)-1-(1-(4-Fluorophenyl)ethyl)piperazine; (R)-1-(4-Fluoro-α-methylbenzyl)piperazine; (R)-1-(1-(p-Fluorophenyl)ethyl)piperazine; (R)-N-[(4-Fluorophenyl)ethyl]piperazine; (R)-α-Methyl-4-fluorobenzylpiperazine; (R)-1-(4-Fluorobenzylhydryl)piperazine; 862270-48-2
EINECS	Contact for details

Quality Control

Our (R)-1-(1-(4-Fluorophenyl)Ethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.