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R-3,3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate CAS NO 861909-53-7
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CAS No.:861909-53-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R-3,3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a highly effective chiral ligand and catalyst precursor, enabling the production of enantiomerically pure compounds critical to modern pharmaceuticals and fine chemicals. This product is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and specialty chemical industries where asymmetric synthesis is paramount.
Application
- As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, coupling, and addition reactions.
- As a key precursor for constructing complex chiral catalysts used in pharmaceutical intermediate synthesis.
- In the research and development of novel catalytic systems for the production of enantiomerically pure active pharmaceutical ingredients (APIs).
- For method development and optimization in academic and industrial laboratories focused on stereoselective synthesis.
- In the manufacture of specialty fine chemicals and advanced materials requiring high optical purity.
- As a reference standard for analytical method development and quality control in chiral compound production.
Basic Information
| Product Name | R-3,3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate |
| CAS No. | 861909-53-7 |
| Molecular Formula | C46H36O4P |
| Molecular Weight | 683.75 g/mol |
| Synonyms | (R)-3,3'-Bis(3,5-dimethylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Bis(3,5-xylyl)-BINOL phosphate; (R)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diyl hydrogen phosphate; R-DM-BINAP Acid Phosphate; R-3,3'-Di(3,5-dimethylphenyl)-BINOL Hydrogen Phosphate; (R)-DM-BINAP(O)OH; Chiral Binaphthyl-Derived Phosphoric Acid Ligand; Contact for additional synonyms. |
| EINECS | Contact for details |
Quality Control
Our production of R-3,3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, which is critical for catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess (ee), and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider the use of desiccants or an inert atmosphere to maintain product integrity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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