Description

(R)-3,3'-Bis(3,5-Di-tert-Butylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a high-purity, chiral organophosphorus compound that serves as a sophisticated ligand and catalyst precursor in advanced chemical synthesis. Its value lies in its ability to impart exceptional enantioselectivity in asymmetric transformations, a critical factor for producing optically pure intermediates in regulated industries. This product is essential for research and development chemists and process engineers working in pharmaceutical development, agrochemical synthesis, and the manufacture of fine chemicals where stereochemical control is paramount.

Application

• Asymmetric Catalysis: As a key ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other catalytic cycles.
• Pharmaceutical Intermediates: Synthesis of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: Development of chiral polymers, liquid crystals, and advanced functional materials with specific optical properties.
• Methodology Development: Used in academic and industrial R&D to discover and optimize new asymmetric synthetic protocols.
• Chiral Resolution: Potential application in the separation of racemic mixtures via diastereomeric salt formation or chiral stationary phases.

Basic Information

Product Name	(R)-3,3'-Bis(3,5-Di-tert-Butylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	861909-39-9
Molecular Formula	C54H61O4P
Molecular Weight	829.03 g/mol
Synonyms	(R)-3,3'-Bis(3,5-di-tert-butylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-DTB-BINAP Hydrogenphosphate; (R)-3,3'-Bis(3,5-di-tert-butylphenyl)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl hydrogenphosphate derivative; (R)-BINAP derivative with 3,5-di-tert-butylphenyl groups; (R)-DTB-BINAP-HPO4; Chiral binaphthyl phosphoric acid ligand; (R)-BINOL-based phosphoric acid ligand; Asymmetric organocatalyst precursor.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral chemicals to ensure batch-to-batch consistency and high enantiomeric purity. Production adheres to cGMP guidelines where applicable, and all materials are fully characterized. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, chiral purity (enantiomeric excess), and identity confirmation via advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.