Description

4-Aminoacetophenone-13C is a stable isotope-labeled analog of 4-aminoacetophenone, where the carbonyl carbon is replaced with carbon-13. This compound is a crucial building block in the synthesis of isotopically labeled molecules for advanced analytical and research applications. It is primarily utilized by pharmaceutical, agrochemical, and academic research laboratories engaged in drug metabolism studies (DMPK), quantitative bioanalysis, and the development of internal standards for mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering internal standard for the precise quantification of 4-aminoacetophenone and related metabolites in complex biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK): Used as a tracer in mass spectrometry-based studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical compounds.
• Synthetic Intermediate: Acts as a labeled precursor in the synthesis of more complex carbon-13 labeled compounds for research in medicinal chemistry and chemical biology.
• Environmental and Food Safety Analysis: Employed in the development of analytical methods for detecting trace levels of specific contaminants or residues where high specificity and accuracy are required.
• NMR Spectroscopy: Useful as a chemical shift reference or probe in nuclear magnetic resonance (NMR) studies due to the distinct signal of the carbon-13 label.

Basic Information

Item	Details
Product Name	4-Aminoacetophenone-13C
CAS No.	861435-57-6
Molecular Formula	C713CH9NO
Molecular Weight	137.15 g/mol (approx.)
Synonyms	1-(4-Aminophenyl)ethanone-1-13C; 4'-Aminoacetophenone-1-13C; p-Aminoacetophenone-13C; 4-Acetylaniline-13C; 1-(4-Aminophenyl)-1-13C-ethanone; 4-Aminoacetophenone (carbonyl-13C); 4-AAP-13C; [1-13C]-4-Aminoacetophenone
EINECS	Contact for details

Quality Control

Our 4-Aminoacetophenone-13C is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of analytical and synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to rigorous quality management protocols to guarantee batch-to-batch consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.