Description

4-Iodo-Piperidine is a valuable halogenated piperidine derivative, serving as a versatile building block in advanced organic synthesis. Its core value lies in providing a reactive iodine handle for cross-coupling reactions and as a key intermediate for introducing the piperidine pharmacophore. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. The product is supplied under the identifier CAS NO 860765-00-0.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine atom facilitates pivotal transformations like Suzuki, Negishi, and Stille couplings to form carbon-carbon bonds.
• Medicinal Chemistry & SAR Studies: Critical for structure-activity relationship studies to optimize the biological activity of lead compounds.

Basic Information

Product Name	4-Iodo-Piperidine
CAS No.	860765-00-0
Molecular Formula	C5H10IN
Molecular Weight	211.05 g/mol
Synonyms	4-Iodopiperidine; Piperidine, 4-iodo-; 4-Iodo-piperidine; 4-Iodopiperidine hydrochloride (salt form); 860765-00-0; 4-IP; Iodopiperidine
EINECS	Contact for details

Quality Control

Our 4-Iodo-Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity against stringent in-house specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.