Description

2-Bromo-3-Iodopyrazine is a high-purity halogenated pyrazine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique bifunctional halogen pattern enables precise, sequential cross-coupling reactions, making it indispensable for constructing complex heterocyclic architectures. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with specific modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, allowing for the sequential introduction of diverse aryl and alkyl groups.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable tool in academic and industrial laboratories for methodology development and exploring new chemical space.

Basic Information

Product Name	2-Bromo-3-Iodopyrazine
CAS No.	860308-71-0
Molecular Formula	C4H2BrIN2
Molecular Weight	284.88 g/mol
Synonyms	3-Iodo-2-bromopyrazine; Pyrazine, 2-bromo-3-iodo-; 2-Bromo-3-iodo-pyrazine; 860308-71-0; 2-Brom-3-jodpyrazin; 2-Bromo-3-iodopyrazine (Halogenated Pyrazine)
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Iodopyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.