Description

n-1-Boc-2-Phenylpiperazine is a high-purity, protected piperazine derivative widely used as a critical pharmaceutical intermediate. Its primary value lies in providing a versatile nitrogen-containing scaffold for the synthesis of complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing new therapeutic agents, including central nervous system (CNS) drugs and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry for lead optimization.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group allows for selective protection of the secondary amine during multi-step synthetic sequences.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex organic molecules for agrochemical and material science applications.
• Library Synthesis: Serves as a core structure for generating diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	n-1-Boc-2-Phenylpiperazine
CAS No.	859518-32-4
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	1-Boc-2-Phenylpiperazine; tert-Butyl 2-phenylpiperazine-1-carboxylate; 2-Phenyl-1-(tert-butoxycarbonyl)piperazine; 1-N-Boc-2-phenylpiperazine; N-Boc-2-phenylpiperazine; 1-(tert-Butoxycarbonyl)-2-phenylpiperazine; Boc-2-phenylpiperazine
EINECS	Contact for details

Quality Control

Our n-1-Boc-2-Phenylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.