Description

1-n-Boc-2-Isobutylpiperazine is a high-purity, protected piperazine derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceutical candidates, particularly in medicinal chemistry for creating complex molecular architectures. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality raw materials for API development and process R&D.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in the design and construction of novel heterocyclic compounds for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetics Synthesis: Serves as a constrained scaffold or a backbone component in the development of peptide mimics with enhanced metabolic stability.
• Agrochemical Development: Employed as an intermediate in the research and production of advanced crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Utilized for synthesizing specialized ligands for metal catalysis or as a precursor for chiral auxiliaries.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-n-Boc-2-Isobutylpiperazine
CAS No.	859518-31-3
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-2-(2-Methylpropyl)piperazine; tert-Butyl 2-isobutylpiperazine-1-carboxylate; 2-Isobutyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-2-isobutylpiperazine; N-Boc-2-isobutylpiperazine; Boc-2-isobutylpiperazine; 859518-31-3
EINECS	Contact for details

Quality Control

Our 1-n-Boc-2-Isobutylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant regulatory frameworks for our customers' specific end-use requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.