Description

tert-Butyl 3-(Hydrazinecarbonyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups—a Boc-protected amine and a hydrazinecarboxamide moiety—which enable precise and versatile chemical transformations. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including protease inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Used in the research and production of inhibitors for various proteases, including viral proteases.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for creating peptide-like molecules with enhanced metabolic stability.
• Agrochemical Research: Employed in the discovery of new herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP conditions.

Basic Information

Product Name	tert-Butyl 3-(Hydrazinecarbonyl)Piperidine-1-Carboxylate
CAS No.	859154-32-8
Molecular Formula	C11H21N3O3
Molecular Weight	243.30 g/mol
Synonyms	1-Boc-3-(hydrazinecarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-3-(hydrazinecarbonyl)piperidine; 3-(Hydrazinecarbonyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(hydrazinecarbonyl)piperidine-1-carboxylate; 1-Boc-piperidine-3-carbohydrazide; 1-N-Boc-3-piperidinecarbohydrazide; 3-Carbohydrazidopiperidine-1-carboxylic acid tert-butyl ester; Piperidine-1,3-dicarboxylic acid, 3-hydrazide, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Hydrazinecarbonyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production can be aligned with cGMP guidelines for applications requiring the highest regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.