Description

2-Bromo-6-Cyanopyrazine CAS NO 859064-02-1 is a versatile and high-value heterocyclic building block used in advanced organic synthesis. Its unique structure, featuring both bromine and cyano functional groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Nucleophilic Substitution: The cyano group can be further transformed into amides, acids, or reduced to amines, expanding its utility.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-6-Cyanopyrazine
CAS No.	859064-02-1
Molecular Formula	C5H2BrN3
Molecular Weight	183.99 g/mol
Synonyms	6-Bromo-2-cyanopyrazine; 2-Cyano-6-bromopyrazine; Pyrazine, 2-bromo-6-cyano-; 859064-02-1; 2-Bromo-6-cyanopyrazine; 6-Bromopyrazine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Cyanopyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.