Description

3-Bromo-4-[(4-Methylpiperazin-1-Yl)Methyl]Aniline is a high-value, multi-functional aromatic amine derivative featuring a bromine substituent and a methylpiperazine moiety. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) in the synthesis of complex bioactive molecules, particularly in oncology and CNS drug discovery. It is essential for research institutions and manufacturers engaged in developing small molecule therapeutics and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted cancer therapies.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides and fungicides with specific activity.
• Material Science: Precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Research: Serves as a versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination).

Basic Information

Product Name	3-Bromo-4-[(4-Methylpiperazin-1-Yl)Methyl]Aniline
CAS No.	859027-13-7
Molecular Formula	C12H18BrN3
Molecular Weight	284.20 g/mol
Synonyms	1-(3-Bromo-4-aminobenzyl)-4-methylpiperazine; 4-[(4-Methyl-1-piperazinyl)methyl]-3-bromoaniline; 3-Bromo-4-[(4-methyl-1-piperazinyl)methyl]benzenamine; 3-Bromo-4-((4-methylpiperazin-1-yl)methyl)aniline; 859027-13-7; Benzenamine, 3-bromo-4-[(4-methyl-1-piperazinyl)methyl]-; 3-Bromo-4-(4-methylpiperazine-1-ylmethyl)aniline
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-4-[(4-Methylpiperazin-1-Yl)Methyl]Aniline adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flame, and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.