Description

2-(3-Hydroxypiperidin-1-Yl)Acetonitrile is a versatile nitrile-functionalized piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a hydroxyl group and a nitrile moiety on a piperidine scaffold, makes it highly valuable for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides where specific stereochemistry is required for activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke, multi-step synthetic routes.

Basic Information

Product Name	2-(3-Hydroxypiperidin-1-Yl)Acetonitrile
CAS No.	857636-97-6
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	1-(Cyanomethyl)-3-hydroxypiperidine; 3-Hydroxy-1-piperidineacetonitrile; 2-(3-Hydroxy-1-piperidinyl)acetonitrile; 2-(3-Hydroxypiperidino)acetonitrile; 3-Hydroxypiperidine-1-acetonitrile; (3-Hydroxypiperidin-1-yl)acetonitrile; 1-Piperidineacetonitrile, 3-hydroxy-
EINECS	Contact for details

Quality Control

Our production of 2-(3-Hydroxypiperidin-1-Yl)Acetonitrile adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical purity and consistency, with a focus on meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA), detailing identity, purity (typically by HPLC), and impurity profile, is provided with every shipment to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.