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4-(4-Bromophenyl)-4-(4-Chlorophenyl)Piperidine CAS NO 857531-01-2


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CAS No.:857531-01-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(4-Bromophenyl)-4-(4-Chlorophenyl)Piperidine is a high-purity, functionalized piperidine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique bifunctional aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and receptor-targeted therapies.
  • Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated aromatic groups for bioactivity.
  • Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
  • Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for creating diverse chemical libraries in medicinal chemistry.
  • Academic & Institutional Research: A valuable tool for studying reaction mechanisms and developing new synthetic methodologies in university and R&D laboratory settings.

Basic Information

Product Name 4-(4-Bromophenyl)-4-(4-Chlorophenyl)Piperidine
CAS No. 857531-01-2
Molecular Formula C17H17BrClN
Molecular Weight 350.68 g/mol
Synonyms 4-(4-Bromophenyl)-4-(4-chlorophenyl)piperidine; 4-(p-Bromophenyl)-4-(p-chlorophenyl)piperidine; 1-(4-Bromophenyl)-1-(4-chlorophenyl)-4-piperidinyl; 4,4-Bis(4-halophenyl)piperidine derivative; NSC 405124; 4-(4'-Chlorophenyl)-4-(4''-bromophenyl)piperidine; 4-(4-Chlorophenyl)-4-(4-bromophenyl)piperidine
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Quality Control

Our 4-(4-Bromophenyl)-4-(4-Chlorophenyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Any single unknown impurity ≤ 0.5%
Residual Solvents (GC) Complies with ICH Q3C
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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