Description

Bis(Hexamethyldisilazido)Magnesium, Mg(HMDS)2 is a highly reactive organomagnesium compound primarily used as a powerful, non-nucleophilic base and a versatile precursor in advanced chemical synthesis. Its core value lies in its ability to efficiently deprotonate a wide range of weakly acidic substrates under mild conditions, enabling the production of high-value intermediates. This specialty chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing complex molecular architectures where precise control over reactivity is paramount.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the deprotonation and functionalization of sensitive heterocycles, amides, and other pharmacologically active compounds.
• Polymer & Materials Science: Used as an initiator or catalyst in the polymerization of olefins and in the surface modification of inorganic materials.
• Agrochemical Manufacturing: Employed in the synthesis of complex active ingredients that require selective deprotonation steps.
• Precursor for Magnesium-Containing Films: Serves as a volatile source in chemical vapor deposition (CVD) and atomic layer deposition (ALD) processes for electronic and optical coatings.
• Organic Synthesis & Methodology Development: A staple in research laboratories for constructing carbon-carbon and carbon-heteroatom bonds under anhydrous conditions.
• Lithium-Ion Battery Research: Investigated as a potential electrolyte additive or precursor for protective surface layers on electrodes.

Basic Information

Item	Detail
Product Name	Bis(Hexamethyldisilazido)Magnesium
CAS No.	857367-60-3
Molecular Formula	C12H36MgN2Si4
Molecular Weight	353.06 g/mol
Synonyms	Magnesium bis(hexamethyldisilazide); Mg(HMDS)2; Magnesium Hexamethyldisilazide; Bis(trimethylsilyl)amido Magnesium; Magnesium bis[bis(trimethylsilyl)amide]; Magnesium 1,1,1,3,3,3-hexamethyldisilazan-2-ide; (TMS)2NMgN(TMS)2; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our production of Bis(Hexamethyldisilazido)Magnesium adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including assay determination and impurity profiling, to meet the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and key parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Always handle and open containers in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Assay (Mg content)	≥ 95.0%
Purity (by NMR)	≥ 98.0%
Solubility	Soluble in common organic solvents (e.g., THF, toluene, hexanes)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.